Evaluation Of The Biocidal Activity And Chemical Identification Of Valepotriates In Four Species Popularly Recognized In Guatemala As Valerian
DOI:
https://doi.org/10.54495/Rev.Cientifica.EdicionEspecial2005.202%20Keywords:
Evaluation, Bocidal activity, Chemical identification, Valepotriates, Guatemala, ValerianAbstract
The study of four plants is reported, three of them are popularly called valerian in Guatemala, due to the sedative property they supposedly possess, these plants are Vetiveria zizatiioides L., Chaptalia nutans L., Perezia nudicaulis Gray. The fourth plant is Valeriana prionophylla Stand!, belonging to the genus Valeriana and used for the same purpose.
The main objective of the research was the chemical identification of valerenic acid and hydroxvalerenic acid, in plants popularly called Valerian, since these metabolites are specific for the Valerian genus and are what give it its sedative effect. Additionally, other valepotriates such as valtrate, didrovaltrate and acevaltrate were identified. The root of Valeriana officinalis L. was used as standard, while E prionophylla was included in the study. plant in Guatemala without studies carried out so far. The chemical identification was carried out by means of thin layer chromatography, resulting in the presence of these molecules in the root of the plants called Valeriana, being more abundant in the root of C. nutans, followed by V zizanioides and finally P. nudicaulis. The root of V. prionophylla showed the presence of bands characteristic of valepotriates as expected, but it was still larger than E officinalis.
Another objective was the evaluation of the antibacterial, antifungal and insecticidal activity of the plants under study. These analyzes were performed in two phases. The first was the lamiz.aje with cultured microorganisms, exposed to the extract of the roots of the plants at a concentration of 1 mg/mL. The second (carried out if the extract inhibits the growth of microorganisms at 1 mg/mL) consisted of determining the minimum inhibitory concentration (MIC) at concentrations of 1, 0.5 and 0.25 mg/mL. Being four inactive plants except P. nudicaulis and E prionophylla active against Cryplococcus neoformans at 0.5 and 0.25 mg/mL respectively.
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Copyright (c) 2005 Ada Cruz, Sully M. Cruz, Isabel Gaitán, Armando Cáceres
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