Association between the presence of Helicobacter pylori and gastric pathology detected by endoscopy

Authors

  • L. Alonzo Escuela de Química Biológica, Facultad de Ciencias Químicas y Farmacia, Universidad de San Carlos de Guatemala
  • G. Arroyo Escuela de Química Biológica, Facultad de Ciencias Químicas y Farmacia, Universidad de San Carlos de Guatemala
  • M. Benito Escuela de Química Biológica, Facultad de Ciencias Químicas y Farmacia, Universidad de San Carlos de Guatemala
  • A. Duarte Escuela de Química Biológica, Facultad de Ciencias Químicas y Farmacia, Universidad de San Carlos de Guatemala
  • V. Matta Escuela de Química Biológica, Facultad de Ciencias Químicas y Farmacia, Universidad de San Carlos de Guatemala
  • F. Nave Escuela de Química Biológica, Facultad de Ciencias Químicas y Farmacia, Universidad de San Carlos de Guatemala
  • L. Pernilla Escuela de Química Biológica, Facultad de Ciencias Químicas y Farmacia, Universidad de San Carlos de Guatemala
  • S. Polanco Escuela de Química Biológica, Facultad de Ciencias Químicas y Farmacia, Universidad de San Carlos de Guatemala
  • G. Rodas Escuela de Química Biológica, Facultad de Ciencias Químicas y Farmacia, Universidad de San Carlos de Guatemala
  • R. Ruiz Escuela de Química Biológica, Facultad de Ciencias Químicas y Farmacia, Universidad de San Carlos de Guatemala

DOI:

https://doi.org/10.54495/Rev.Cientifica.EdicionEspecial2009.178%20

Keywords:

Helicobacter pylori, Endoscopy, Biopsy, Gastritis

Abstract

In order to determine the relationship between the presence of Helicobacter pylori in biopsy and gastric pathologies detected by endoscopy, this research was carried out. For this, data was collected from 1468 patients who underwent this procedure and who underwent gastric biopsy in search of the bacteria.


The data collection was carried out by consulting the medical records of the patients evaluated by the gastroenterologists who collaborated with the present study and information was obtained about: age, gender, diagnosis and presence or absence of Helicobacter pylori in the biopsy performed.

Of the total of 1468 patients, it was found that 536 (36.5%) were men and 932 (63.5%) women. Results for Helicobacter pylori were positive in 778 patients (53%) and negative in 690 (47%). The gastric pathology that was most frequently observed was non-atrophic chronic gastritis in 415 patients (28.2%) followed by gastritis not specified by the doctor in 294 patients. The age range in which there was a higher proportion of Helicobacter pylori infection was 41 to 50 years, finding no difference between the presence of Helicobacter pylori and gender.


It is considered important and necessary that a standard classification be used in Guatemala for future studies, such as the Sydney classification to determine the presence of Helicobacter pylori and its consequent implication in the development of gastric pathology, especially cancer.


In conclusion, 53% of the patients who underwent endoscopy had a positive result for the presence of Helicobacter pylori (778/1468), a fairly high percentage that correlates with the percentage of positivity found in the population.

Downloads

Download data is not yet available.

References

Schwizer W, et al. Helicobacter pylori and symptomatic relapse of gastro-oesophageal reflux disease: a randomised controlled trial.Lancet 2001; Págs. 1738-1742pp, https://doi.org/10.1016/S0140-6736(00)04894-7

Dunn B, Cohen H, Blaser M. Helicobacter pylori. Clin. Microbiol Rev. 1997.10 (4):720-741, https://doi.org/10.1128/CMR.10.4.720

Hernández M. Helicobacter pylori. La bacteria que más infecta al ser humano. Rev Cubana Aliment Nutr . 2001. 15 (1): 42-54.

Salgueiro J et al. Review article: is there a link between micronutrient malnutrition and Helicobacter pylori infection?. Aliment Pharmacol Ther 2004; 20:1029-1034, https://doi.org/10.1111/j.1365-2036.2004.02265.x

Khorrami S, et al. Helicobacter pylori eradication and prevention of recurrent hemorrhage from peptic ulcer. A meta- analysis. NEJM .Gut 2001; 49; (Suppl2), A61.

International Agency for Research on cancer. Schistosomes, liver flukes and Helicobacter pylori. Lyon: JARG. 1994;61:177-241.

NIH Consensus Conference. Helicobacter pylori in peptic ulcer disease. NHI Consensus Development Panel on Helicobacter pylori in peptic ulcer disease. JAMA.1994; 272:65-69, https://doi.org/10.1001/jama.272.1.65

Hernández M. Helicobacter pylori. La bacteria que más infecta al ser humano. Rev Cubana Aliment Nutr 2001:15 (1): 42-54.

Eurogast Study Group. An international association between Helicobacter pylori infection and gastric cancer. Lancet. 1994.341:1359-62, https://doi.org/10.1016/0140-6736(93)90938-D

Graham DY. Evolution of concepts regarding Helicobacter pylori: from a cause gastritis to a public health problem. Am. J. Gastroenterol.1994;89(4):469-72.

Gisbert J y Pajares García J. Tratamiento de las enfermedades gastroenterológicas. Doc. Tec. AEG. 2004 octubre. 30 pp.

Breuer TH, Malaty D &raham Y. The epidemiology of H. pylori-associated gastroduodenal diseases. En: Ernst PB, Michetti P, Smith D. The Immunobiology of H. pylori: from pathogenesis to prevention. Lippincott-Raven Publishers. Philadelphia. 1997. Pp 1-14.

Asaka M et al. Gastric cáncer. En. Mobley LT, Menz GL and Hazelli SL. Helicobacter pylori: physiology and genetics. American Society for Microbiology Press, Washington DC. 2001. Pp 481-498, https://doi.org/10.1128/9781555818005.ch40

Tachiro J et al. Gastric cancer detected after Helicobacter pylori erradication. Digestive Endoscopy. 2007; 19:167-173, https://doi.org/10.1111/j.1443-1661.2007.00749.x

Huang JQ, et al. Metanalysis of the relationship between CagA seropositivity and gastric cáncer. Gastroenterology. 2003;125:1636, https://doi.org/10.1053/j.gastro.2003.08.033

Sipponen P, Kekki M, Siurala M. The Sydney System: epidemiology an natural history of chronic gastritis. J. Gastroenterol Hepatol. 1991;6: 244-51, https://doi.org/10.1111/j.1440-1746.1991.tb01472.x

Sipponen P, Riihelä M, Hvvärinen H, Seppälä K. Chronic nonatrophic (“superficial”) gastritis increases the risk of gastric carcinoma. Scand. J. Gastroenterol. 1994:29:336-40, https://doi.org/10.3109/00365529409094845

Published

2009-12-31

How to Cite

Alonzo, L., Arroyo, G., Benito, M., Duarte, A., Matta, V., Nave, F., Pernilla, L., Polanco, S., Rodas, G., & Ruiz, R. (2009). Association between the presence of Helicobacter pylori and gastric pathology detected by endoscopy. Revista Científica, 34–40. https://doi.org/10.54495/Rev.Cientifica.EdicionEspecial2009.178

Issue

Section

Artículos originales

Most read articles by the same author(s)

1 2 > >>