Validation of Analytical Methodology to Determine the Antioxidant Capacity of Raw Materials Used in the Oily Phase of Cosmetic Emulsions

Abstract

The validation of analytical methodology to determine the autoxidative capacity in fatty substances used in the oily phase of cosmetic creams, was carried out on pure raw materials and subjected to autoxidation processes, divided into two classes: studies at ambient conditions, in stability chambers at 37ºC , 45ºC and through the accelerated autoxidation method proposed by Jacquisblieva and Popov.

The main objective of this research work was to design and validate an analytical methodology to predict, in a determined time, the auto-oxidation capacity for a fat and that the results would be exact, precise and reliable.

The substances analyzed were: triple pressed stearic acid, glyceryl monostearate, anhydrous lanolin and cocoa butter. According to the results, it was observed that the methodology is applicable to study the autooxidative behavior of anhydrous lanolin and cocoa butter. It was shown that stearic acid and glyceryl monostearate do not generate reliable, precise and exact results, with the methodology under study.