Interface interactions between biological vesicles and inorganic surfaces of biomaterials using atomic force microscopy.

Authors

  • F. Solera Laboratorio Nacional de Nanotecnología. Centro Nacional de Alta Tecnología. Consejo Nacional de Rectores
  • J. Vega Laboratorio Nacional de Nanotecnología. Centro Nacional de Alta Tecnología. Consejo Nacional de Rectores
  • S. Madrigal Laboratorio de Polímeros. Escuela de Química. Universidad Nacional
  • A. Loria Instituto de Investigaciones Farmacéuticas. Faculta de Farmacia. Universidad de Costa Rica

DOI:

https://doi.org/10.54495/Rev.Cientifica.v22i1.125

Keywords:

Interface, biological vesicles, biomaterials, atomic force microscopy, liposome

Abstract

Interface incompatibilities in the interaction between biological microparticles that normally circulate in the
blood and the surface of biomaterials implants are normally associated with subsequent rejection reactions
by the immune system. This requires an explanatory model for the behavior observed at the interface of
liposomes and platelets in contact with biomaterials and inorganic surfaces. Thus, allowing the analysis of
the relationship between the ionic balance of surface forces of attraction between liposome-surface/degree
of deformation and change in the surface properties of liposomal nanoparticles absorbed by the surface
modification of liposomes with biopolymers such as chitosan. Progress has been made in understanding the
dynamics of interfaces for consistency of different lipids vesicles as a model and found that the biopolymer
coating of lipid vesicles with chitosan provides better physical stability and an increase in the interface between
biomaterials and biomimetic inorganic nanoparticles.

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Published

2012-12-31

How to Cite

Solera, F., Vega, J., Madrigal, S., & Loria, A. (2012). Interface interactions between biological vesicles and inorganic surfaces of biomaterials using atomic force microscopy. Revista Científica, 22(1), 73–80. https://doi.org/10.54495/Rev.Cientifica.v22i1.125

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Artículos originales